Logo der Universität Wien

Publikationen Barbara Lieder (geb. Rohm)




Liszt KI, Ley JP, Lieder B, Behrens M, Stöger V, Reiner A, Hochkogler CMH, Köck E, , Marchiori A, Hans J, Widder S, Krammer G, Gareth JS, Somoza MM, Meyerhof W, Somoza V. Caffeine induces gastric acid secretion via bitter taste signaling in gastric parietal cells. PNAS, June 2017 (web), doi: 10.1073/pnas.1703728114

Lieder B, Zaunschirm M, Holik AK, Ley JP, Hans J, Krammer GE, Somoza V. The Alkamide trans-Pellitorine Targets PPARγ via TRPV1 and TRPA1 to Reduce Lipid Accumulation in Developing 3T3-L1 Adipocytes, May 2017, Frontiers in Pharmacology, doi. 10.3389/fphar.2017.00316 

Lieder B, Hoi JK, Holik AK, Geissler T, Geissler K, Hans J, Friedl B, Liszt K, Krammer G, Ley JP, Somoza V, The flavanon homoeriodictyol increases SGLT-1 mediated glucose-uptake but decreases serotonin release in differentiate Caco-2 cells. PLoS One.2017, doi:10.1371/journal pne.0171580

Obst K, Lieder B, Reichelt KV, Backes M, Paetz S, Geißler K, Krammer G, Somoza V, Ley JP, Engel KH Sensory active piperine analogues from Macropiper exelsum and their effects on interstinal nutrient uptake in Caco-2 cell, Phytochemistry 2017 March; 135:181-190, doi: 10.1016/j.phytochem.2016.12.016, PMID:28065397

Walker J, Ley JP, Schwerzler J, Lieder B, Beltran L, Ziemba PM, Hatt H, Hans J, Widder S, Krammer GE, Somoza V (2017) Nonivamide, a casaicin analogue, exhibits anti-inflammatory properties in peripheral blood mononuclear and U-937 macrophages, Mol Nutr Food Res. 2017 doi: 10.1002/mnfr201600474.

Hochkoger CM, Lieder B, Rust P, Berry D, Meier S, Pignitter M, Riva A, Leitinger A, Bruk A, Wagner S, Hans J, Widder S, Ley JP, Krammer G, Somoza V, A 12-week intervention with nonivamide, a TRPV1 agonist, prevents a dietary-induced body fat gain and increases peripheral serotonin in moderately overweight subjects. Mol Nutr Food Res. 2017, doi:10.1002/mnfr.201600731


Holik AK, Lieder B, Kretschy N, Somoza M, Held S, Somoza V. (2016) Nϵ Carboxymethyllysine Increases the Expression of miR-103/143 and Enhances Lipid Accumulation in 3T3-L1 Cells, J Cell Biochem 2016 Oct. 2143-22. doi:101002/jcb.25576


 Rohm, B., A.K. Holik, N. Kretschy, M.M. Somoza, J.P. Ley, S. Widder, G.E. Krammer, D. Marko, and V. Somoza, Nonivamide Enhances miRNA let-7d Expression and Decreases Adipogenesis PPARgamma Expression in 3T3-L1 Cells. J Cell Biochem, 2015. 116(6): p. 1153-63. doi: 10.1002/jcb.25052.

 Rohm, B., A. Riedel, J.P. Ley, S. Widder, G.E. Krammer, and V. Somoza, Capsaicin, nonivamide and trans-pellitorine decrease free fatty acid uptake without TRPV1 activation and increase acetyl-coenzyme A synthetase activity in Caco-2 cells. Food Funct, 2015. 6(1): p. 173-85. doi: 10.1039/c4fo00435c.


 Hochkogler, C.M., B. Rohm, K. Hojdar, M. Pignitter, S. Widder, J.P. Ley, G.E. Krammer, and V. Somoza, The capsaicin analog nonivamide decreases total energy intake from a standardized breakfast and enhances plasma serotonin levels in moderately overweight men after administered in an oral glucose tolerance test: a randomized, crossover trial. Mol Nutr Food Res, 2014. 58(6): p. 1282-90. doi: 10.1002/mnfr.201300821.

 Riedel, A., R. Lang, B. Rohm, M. Rubach, T. Hofmann, and V. Somoza, Structure-dependent effects of pyridine derivatives on mechanisms of intestinal fatty acid uptake: regulation of nicotinic acid receptor and fatty acid transporter expression. J Nutr Biochem, 2014. 25(7): p. 750-7. doi: S0955-2863(14)00056-4 [pii] 10.1016/j.jnutbio.2014.03.002.


 Holik, A.K*., B. Rohm*, M.M. Somoza, and V. Somoza, N(epsilon)-Carboxymethyllysine (CML), a Maillard reaction product, stimulates serotonin release and activates the receptor for advanced glycation end products (RAGE) in SH-SY5Y cells. Food Funct, 2013. 4(7): p. 1111-20. doi: 10.1039/c3fo60097a. *equally contribution

 Rohm, B., A.K. Holik, M.M. Somoza, M. Pignitter, M. Zaunschirm, J.P. Ley, G.E. Krammer, and V. Somoza, Nonivamide, a capsaicin analog, increases dopamine and serotonin release in SH-SY5Y cells via a TRPV1-independent pathway. Mol Nutr Food Res, 2013. 57(11): p. 2008-18. doi: 10.1002/mnfr.201200846.

 Sack, M., N. Kretschy, B. Rohm, V. Somoza, and M.M. Somoza, Simultaneous light-directed synthesis of mirror-image microarrays in a photochemical reaction cell with flare suppression. Anal Chem, 2013. 85(18): p. 8513-7. doi: 10.1021/ac4024318.


 Moebius, N., C. Ross, K. Scherlach, B. Rohm, M. Roth, and C. Hertweck, Biosynthesis of the respiratory toxin bongkrekic acid in the pathogenic bacterium Burkholderia gladioli. Chem Biol, 2012. 19(9): p. 1164-74. doi: S1074-5521(12)00280-3 [pii] 10.1016/j.chembiol.2012.07.022.

 Riedel, A., M. Pignitter, C.M. Hochkogler, B. Rohm, J. Walker, G. Bytof, I. Lantz, and V. Somoza, Caffeine dose-dependently induces thermogenesis but restores ATP in HepG2 cells in culture. Food Funct, 2012. 3(9): p. 955-64. doi: 10.1039/c2fo30053b.

 Walker, J., B. Rohm, R. Lang, M.W. Pariza, T. Hofmann, and V. Somoza, Identification of coffee components that stimulate dopamine release from pheochromocytoma cells (PC-12). Food Chem Toxicol, 2012. 50(2): p. 390-8. doi: S0278-6915(11)00535-7 [pii] 10.1016/j.fct.2011.09.041.


 Rohm, B., K. Scherlach, and C. Hertweck, Biosynthesis of the mitochondrial adenine nucleotide translocase (ATPase) inhibitor bongkrekic acid in Burkholderia gladioli. Org Biomol Chem, 2010. 8(7): p. 1520-2. doi: 10.1039/b925483h.


 Rohm, B., K. Scherlach, N. Mobius, L.P. Partida-Martinez, and C. Hertweck, Toxin production by bacterial endosymbionts of a Rhizopus microsporus strain used for tempe/sufu processing. Int J Food Microbiol, 2010. 136(3): p. 368-71. doi: S0168-1605(09)00532-7 [pii] 10.1016/j.ijfoodmicro.2009.10.010.


        Invited papers in conference proceedings

 Rohm, B., M. Zaunschirm, S. Widder, J. Ley, G. Krammer, and V. Somoza. Neurotransmitter-releasing potency of structural capsaicin-analogs in SH-SY5Y cells. in Proceedings of the 10th Wartburg Symposium . Advances and Challenges in Flavor Chemistry & Biology. 2014. Eisenach: Verlag Deutsche Forschungsanstalt für Lebensmittelchemie,.M.W. Hofmann T, Schieberle P

        Other articles and reports published in international journals

       (Conference Papers)

Liszt, K.I., Ley, J.P., Rohm, B., Stoeger V, Koeck, E., Stuebler, A., Hochkogler, C.M., Somoza, M.M., Widder, S., Hans, J., and Somoza, V.  Caffeine-induced activation of oral and gastric bitter taste receptors regulates gastric acid secretion , Chemical Senses · September 2015 Conference: 37th Annual Meeting of the Association-for-Chemoreception-Sciences, Volume: 40

 Lieder, B., Hochkogler, C.M., Holik, A.-K.,·Somoza M. M.,· Pignitter, M., Ley J.P.·, Widder, S., Krammer, G.E., ·Somoza, V. Implications of the TRPV1 agonist nonivamide for body weight management , Appetite 91 · August 2015, DOI: 10.1016/j.appet.2015.04.016

 Rohm B., Holik , A-K, Kretschy N.,·Somoza M. M., Widder, S.,Ley, J.P., Krammer, G.E., Somoza, V.·The capsaicin-analog nonivamide prevents lipid accumulation via a TRPV1-dependent pathway and regulates related miRNA expression in 3T3-L1 cells , Chemical Senses · January 2014, Conference: 22nd Congress of the European-Chemoreception-Research-Organization, Volume: 39



Institut für Physiologische Chemie
Universität Wien

Althanstrasse 14
Zimmer 2B522-528 & 2B572-579
1090 Wien

T: +43-1-4277-706 01
F: +43-1-4277-9 706
Universität Wien | Universitätsring 1 | 1010 Wien | T +43-1-4277-0