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Research interests

Aims

  • Identification of bioactive food compounds present in our daily diet, and combinations thereof, that are involved in regulatory processes of digestion and satiety (see also CDL for Bioactive Aroma Compounds).
  • Since an excess consumption of nutrients results in metabolic signals that initiate pro-inflammatory responses and damage metabolic homeostasis, the effect of food compounds on metabolic changes that affect pro-inflammatory and pro-oxidative processes in various cell types, e.g. adipocytes or macrophages, are also investigated.
  • In addition to an enhanced micro-inflammatory state, overweight and obese subjects are at high risk for exaggerated acid secretion in the stomach, resulting in digestive discomfort, gastric irritations or gastro-esophageal reflux disease. For overweight people, satiating stomach-soothing foods would support the commonly recommended weight reduction. Therefore, food and food compounds affecting mechanisms of gastric acid secretion in human gastric cancer cells and in healthy subjects are also of interest to us.

 

 

Research approach

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Department of Physiological Chemistry
University of Vienna

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University of Vienna | Universitätsring 1 | 1010 Vienna | T +43-1-4277-0