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Publications of the Christian Doppler Laboratory for Bioactive Aroma Compounds

          Zopun M, Liszt KI, Stoeger V, Behrens M, Redel U, Ley JP, Hans J,
          Somoza  V.  The Human Sweet Receptor T1R3 is Functional in Human
          Gastric  Parietal Tumor Cells (HGT-1) And    Modulates Cyclamate and
          Acesulfame  K-Induced Mechanisms of Gastric Acid Secretion.
  J Agric Food
          Chem
. 2018 Apr 17. doi: 10.1021/acs.jafc.8b00658. accepted

         Hochkogler CM, Lieder B, Schachner D, Heiss E, Schröter A, Hans J, Ley JP,
         Krammer GE, SomozaV (2018) Capsaicin and nonivamide similarly modulate
         outcome measures of mitochondrial energy metabolism in HepG2 and 3Tw-
         L1 cells, Food & Function 9(2):1123-1132 doi:10.1039/c7fo01626

         Holik AK, Lieder B, Kretschy N, Somoza MM, Ley JP, Hans J, Somoza
         V(2018)The  Advanced Glycation End Product Nϵ -Carboxymethyllysine and
         its Precursor Glyoxal Increase SerotoninRelease from Caco-2 cells, Journa lof
        Cellular Biochemistry, 119: 2731--741,    doi:10.1002/jcb.26439

         
Liszt K, Hans J, Ley JP, Köck E, Somoza V (2018) Characterization of
         Bitter Compounds via Modulation of Proton Secretion in Human Gastric
         Parietal Cells in Culture. J Agric Food Chem  66 (10), 2295–2300, doi:
        10.1021/acs.jafc.7b01051

Liszt KI, Ley JP, Lieder B, Behrens M, Stöger V, Reiner A, Hochkogler CMH, Köck E, , Marchiori A, Hans J, Widder S, Krammer G, Gareth JS, Somoza MM, Meyerhof W, Somoza V (2017) Caffeine induces gastric acid secretion via bitter taste signaling in gastric parietal cells. Proc Natl Acad Sci U S A, 140(30), E6260-E6269, doi: 10.1073/pnas.1703728114

           Martinez-Saez N, Hochkogler CM, Somoza V, Dolores del Castillo M (2017) Biscuits with No Added Sugar Containing Stevia, Coffee Fibre and Fructooligosaccharides Modifies α-Glucosidase Activity and the Release of GLP-1 from HuTu-80 Cells and Serotonin from Caco-2 Cells after In Vitro Digestion, Nutrients 9(7), 694, doi: 10.3390/nu9070694

         Hochkogler CM, Liszt K, Lieder B, Stöger V, Stübler A, Pignitter M, Hans J, Widder S,. Ley JP,Krammer GE, Somoza V (2017) Appetite-inducing effects of homoeriodictyol: Two randomized, crossover interventions, Mol Nutr Food Res, 2017, 61 1700459, page 1-9., doi: 0.1002/mnfr.201700459

            Lieder B, Zaunschirm M, Holik AK, Ley JP, Hans J, Krammer GE, Somoza V (2017) The Alkamide trans-Pellitorine Targets PPARγ via TRPV1 and TRPA1 to Reduce Lipid Accumulation in Developing 3T3-L1 Adipocytes. Frontiers in Pharmacology, 8:316 (eCollection), doi: 10.3389/fphar.2017.00316

            Schüller K, Riva A,Pfeiffer S, Berry D, Somoza V (2017) Members of the Oral Microbiota Are Associated with IL-8 Release by Gingival Epithelial Cells in Healthy Individuals. Frontiers in Microbiology, 8:416 (eCollection). doi: 10.3389/fmicb.2017.00416

            Lieder B, Hoi JK, Holik AK, Geissler T, Geissler K, Hans J,  Friedl B, Liszt K, Krammer G, Ley JP, Somoza V. (2017) The flavanon homoeriodictyol increases SGLT-1 mediated glucose-uptake but decreases serotonin release in differentiated Caco-2 cells. PLoS One 12(2):e0171580, doi:10.1371/journal pone.0171580

            Obst K, Lieder B, Reichelt KV, Backes M, Paetz S, Geißler K, Krammer G, Somoza V, Ley JP, Engel KH (2017) Sensory active piperine analogues from Macropiper exelsum and their effects on interstinal nutrient uptake in Caco-2 cells. Phytochemistry 135:181-90. doi: 10.1016/j.phytochem.2016.12.016, PMID:28065397

            Walker J, Ley JP, Schwerzler J, Lieder B, Beltran L, Ziemba PM, Hatt H, Hans J, Widder S, Krammer GE, Somoza V (2017) Nonivamide, a capsaicin analogue, exhibits anti-inflammatory properties in peripheral blood mononuclear cells and U-937 macrophages. Mol Nutr Food Res, Volume 61, Issue 2, Feb. 2017 doi: 10.1002/mnfr201600474

 Hochkogler CM, Lieder B, Rust P, Berry D, Meier S, Pignitter, M, Riva A, Leitinger A, Bruk A, Wagner S, Hans J, Widder S, Ley JP, Krammer G, Somoza V (2017) A 12-week intervention with nonivamide, a TRPV1 agonist, prevents a dietary-induced body fat gain and increases peripheral serotonin in moderately overweight subjects. Mol Nutr Food Res 61, 1600731, doi: 10.1002/mnfr.201600731

 Walker J, Reichelt K, Obst K, Widder S, Hans J, Krammer GE, Ley JP, Somoza  V. (2016) Identification of an anti-inflammatory potential of Herba Santa  (Eriodictyon angustifolium) compounds in human  gingival fibroblasts. Food  and Funct 7:3046-55 doi:10.1039/c6fo00482b

             Holik AK, Lieder B, Kretschy N, Somoza MM, Held S, Somoza V. (2016) Nϵ -Carboxymethyllysine Increases the Expression of miR-103/143 and Enhances Lipid Accumulation in 3T3-L1 Cells. J Cell Biochem 2016 Oct. 2413-22. doi: 10.1002/jcb.25576

            Sack M, Hölz K, Holik AK, Kretschy N, Somoza V, Stengele KP, Somoza MM. (2016) Express photolithographic DNA microarray synthesis with optimized chemistry and high-efficiency photolabile groups. J Nanobiotechnology 14:14. doi: 10.1186/s12951-016-0166-0

  • Rohm B, Zaunschirm M, Widder S, Ley JP, Krammer GE, Somoza V. (2014) Neurotransmitter-releasing potency of structural capsaicin-analogs in SH-SY5Y cells. In: Proceedings of the 10th Wartburg Symposium Eisenach. Advances and Challenges in Flavor Chemistry & Biology. (eds. Hofmann T, Meyerhof W, Schieberle P) Verlag Deutsche Forschungsanstalt für Lebensmittelchemie, p 43-50. 

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